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Effects of Desloratadine and Pseudoephedrine

Prior to the approval of desloratadine and pseudoephedrine in the United States, a number of clinical studies were conducted in several thousand adults and adolescents. In these studies, people taking desloratadine and pseudoephedrine had improved allergy relief compared to the group of people not taking it. This improvement was measured based on a symptom score that looked at changes in the following allergy symptoms:
  • Sneezing
  • Runny nose
  • Itchy nose, ears, and throat
  • Itchy, burning eyes
  • Tearing/watering eyes
  • Redness of eyes
  • Nasal congestion.

Desloratadine and Pseudoephedrine: When and How Do I Take It?

Some general considerations for when and how to take desloratadine and pseudoephedrine include:
  • Desloratadine and pseudoephedrine comes in a tablet. You may take your dose with or without food, but you are recommended to take it with a glass of water. Do not break, chew, or crush the tablets.
  • Desloratadine and pseudoephedrine should be taken at the same time each day to help maintain an even level in the blood. Do not take it more often than directed.
  • The 12-hour dose of desloratadine and pseudoephedrine is usually taken twice a day, while the 24-hour dose is usually taken once a day.
  • For desloratadine and pseudoephedrine to work properly, you have to take it as prescribed. Desloratadine and pseudoephedrine will not work if you stop taking it.

Dosing With Desloratadine and Pseudoephedrine

The dose of desloratadine and pseudoephedrine your healthcare provider recommends will vary, depending on a number of factors, including:
  • Other medical conditions you may have
  • Other medications you may be currently taking.
As with any medication, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Dosing With Desloratadine and Pseudoephedrine for dosing information in adults and children.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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