Drugs Home > Cutivate and Pregnancy
When steroids, including Cutivate (topical fluticasone propionate), were given to pregnant animals, it increased the risk for birth defects and decreased survival rates. Although it is unknown if similar problems would occur in humans, Cutivate should only be used during pregnancy if necessary, at the lowest effective dose, and for the shortest amount of time possible.
Can Pregnant Women Use Cutivate?Cutivate® (topical fluticasone propionate) is a prescription steroid medication that is applied to the skin. At this time, it is unclear if the drug is safe for use during pregnancy. As with most steroids, it should be used only if necessary, at the lowest effective dose, and for the shortest possible time during pregnancy.
What Is Pregnancy Category C?Cutivate is classified as a pregnancy Category C drug. The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been adequately studied in pregnant humans but have caused fetal harm in animal studies.
In addition, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Animal studies have shown that steroids, including Cutivate, may increase the risk for birth defects (such as cleft palate) and may cause other problems, such as poor fetal growth or decreased survival. Similar problems might also occur in humans, although the risk is probably smaller for topical steroids that are applied to the skin like Cutivate.
While short-term use (a few days) of Cutivate applied to a small area of the body is probably not likely to cause problems, extended use or use over a large area of the body should probably be avoided during pregnancy if possible.