Drugs Home > Claforan

A healthcare provider may prescribe Claforan to treat various bacterial infections and to prevent surgical infections. It is given as an injection into a vein or as an intramuscular injection. Your dosage will be calculated based on your age, the severity of the infection, and other medications you are taking, among other factors. Side effects can include nausea, vomiting, or diarrhea.

What Is Claforan?

Claforan® (cefotaxime) is a prescription cephalosporin antibiotic licensed to treat a number of different infections. It is also used to help prevent surgical infections. The medication is given intravenously (by IV) or by intramuscular (IM) injection.
(Click Claforan Uses for more information on this topic, including possible off-label uses.)

Who Makes This Medication?

Brand-name Claforan is made by Baxter Healthcare Corporation for sanofi-aventis U.S., LLC. Generic versions are made by various manufacturers.

How Does Claforan Work?

As mentioned, Claforan is a cephalosporin antibiotic. Cephalosporins are part of a larger group of medications known as beta-lactam antibiotics, named after the ring-like "lactam" structure of these drugs. Claforan works by stopping bacteria from making cell walls, which eventually causes the bacteria to die. Cephalosporins are related to penicillin. Claforan is usually classified as a "third-generation" cephalosporin.

When and How to Use It

Some general considerations to keep in mind during treatment with Claforan include the following:
  • This medication is given by IV or by intramuscular injection. It can be given as a single dose for less serious infections, or it may be given as multiple doses every 4 to 12 hours for more serious infections.
  • For serious infections, it is usually best to give this drug by IV rather than an intramuscular injection.
  • Claforan is often given for a few days after the infection has cleared up. For serious infections, an even longer treatment course may be recommended.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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