Drugs Home > Claforan Side Effects

Researchers have determined that injection site reactions, allergic reactions, and digestive symptoms are some of the most common side effects of Claforan. Fortunately, most people tolerate this antibiotic fairly well, and reactions tend to be minor and easy to treat. However, there are some potentially serious problems, such as bloody diarrhea, seizures, or breathing problems, which your healthcare provider needs to know about right away.

An Introduction to Claforan Side Effects

Just like any medicine, Claforan® (cefotaxime) can cause side effects. However, not everyone who receives the drug will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Claforan. Your healthcare provider can discuss a more complete list with you.)

Possible Side Effects of Claforan

With most medications, studies are performed using both the real drug and a placebo (a "sugar pill" that does not contain any active ingredients) in order to compare the effectiveness and side effects between the real drug and the placebo.
However, studies with Claforan did not use a placebo, as it would be unethical to treat serious infections with a placebo. Therefore, it was up to the researchers to decide which side effects were probably related to the drug.
Common Claforan side effects that were likely to be related to the drug included:
  • Reactions at the injection site (often inflammation for IV use or pain, lumps, and tenderness for IM injections) -- in up to 4.3 percent of people
  • Allergic reactions (usually involving an itchy rash) -- up to 2.4 percent
  • Digestive symptoms (usually diarrhea, but sometimes nausea or vomiting) -- up to 1.4 percent.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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