Certain medications can cause potentially dangerous drug interactions with certolizumab pegol. Taking certolizumab pegol with anakinra can increase your risk of getting an infection. If you receive a "live" vaccination during treatment, you could also become infected with the virus or bacteria from the vaccine. To reduce the risk of interactions, tell your healthcare provider about any other drugs you are taking.
The following sections explain in detail the potentially negative interactions that can occur when certolizumab pegol is combined with any of the drugs listed above.
Abatacept
Combining abatacept with certolizumab pegol may increase the risk of serious infections without providing any additional benefit. These medications should not be combined.
Anakinra (Kineret)
Taking certolizumab pegol with anakinra can increase your risk of getting an infection. In general, these two medications should not be taken together.
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