Drugs Home > Carfilzomib Side Effects

Common Side Effects

Carfilzomib has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people receiving the drug were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
 
In clinical studies, the most common carfilzomib side effects included:
 
  • Fatigue -- in up to 55.5 percent of people
  • Anemia (low red blood cell counts) -- up to 46.8 percent (see Chemotherapy and Anemia)
  • Nausea -- up to 44.9 percent
  • Low platelet counts (which could increase the risk for bleeding) -- up to 36.3 percent (see Blood Clotting Problems and Chemotherapy)
  • Shortness of breath -- up to 34.6 percent
  • Diarrhea -- up to 32.7 percent
  • Fever -- up to 30.4 percent
  • Upper respiratory tract infection (such as the common cold) -- up to 28.3 percent
  • Headache -- up to 27.6 percent
  • Cough -- up to 26 percent.
 
Other common reactions, occurring in 10.3 percent to 24.1 percent of people, included:
 
  • An increase in blood creatinine levels, which could be a sign of kidney problems
  • Swelling of the arms, hands, legs, ankles, or feet
  • Vomiting
  • Constipation
  • A low level of white blood cells, which could increase the risk for infection (see Chemotherapy and Infections)
  • Back pain
  • Insomnia
  • Chills
  • Joint pain
  • High blood pressure (hypertension)
  • Loss of strength and energy
  • Low levels of potassium in the blood (hypokalemia)
  • Low levels of magnesium in the blood (hypomagnesemia)
  • Arm and leg pain
  • Pneumonia
  • Increase in certain liver enzymes, which could be a sign of liver problems
  • Dizziness
  • Reduced sense of touch
  • Loss of appetite
  • General pain
  • High blood sugar levels (hyperglycemia)
  • Chest pain
  • High blood calcium levels (hypercalcemia)
  • Low blood phosphate levels (hypophosphatemia)
  • Low blood sodium levels (hyponatremia).
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation
Advertisement


Topics & Medications

Quicklinks

Related Channels

eMedTV Links
Copyright © 2006-2019 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.