Drugs Home > Brentuximab Vedotin

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to receiving this medication if you have:
  • Been taking a chemotherapy medicine called bleomycin
  • An infection of any kind
  • A weakened immune system due to human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), cancer, or any other cause
  • Anemia
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Brentuximab Vedotin to learn more, including information on who should not receive the drug.)

How Does It Work?

Brentuximab vedotin is a combination of a drug and an antibody (a protein normally made by the immune system that recognizes and attaches to an antigen). The antibody portion of brentuximab vedotin attaches to CD30, an antigen found on the surface of some lymphoma cells. Once attached, brentuximab vedotin enters the cell and releases the drug portion. The drug portion of brentuximab vedotin binds to tubulin, an important protein found inside the cells, causing the cell to die.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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