Drugs Home > Bortezomib

Bortezomib is a chemotherapy drug that works to kill cancer cells in people who have multiple myeloma or mantle cell lymphoma. This medication comes as an injection that is administered by a healthcare provider. Your dosage will depend on several factors, such as your height and weight. Side effects may be serious and can include diarrhea, nausea, and low blood cell counts.

What Is Bortezomib?

Bortezomib (Velcade®) is a prescription chemotherapy medication that belongs to a class of drugs known as proteasome inhibitors. Chemotherapy is a type of cancer treatment that uses medicines to stop or slow down the growth of cancer cells.
Bortezomib is approved to treat multiple myeloma (cancer of the plasma cells). It is also approved to treat mantle cell lymphoma (a cancer of the lymphatic system) in people who have already received at least one other treatment.
(Click What Is Bortezomib Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any chemotherapy medicine, bortezomib can cause side effects, some of which can be quite significant. Talk with your healthcare provider about ways to prevent or treat certain adverse reactions to this medicine.
Common side effects of bortezomib include but are not limited to:
  • Weakness or lack of energy
  • Nausea
  • Diarrhea
  • Low platelet counts
  • Low white blood cell counts
  • Numbness, tingling, burning, or pricking sensations of the arms or feet.
(Click Bortezomib Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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