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Healthcare providers may recommend treatment with bedaquiline in people who have tuberculosis. Due to the potentially serious complications this drug may cause, however, it is only reserved for use in those who have no other treatment options. The tablets are taken once daily for 2 weeks and then three times a week for 22 weeks. Side effects include nausea, headaches, and joint pain.

What Is Bedaquiline?

Bedaquiline (Sirturo™) is a prescription medication approved to treat multidrug-resistant tuberculosis (TB) in combination with other medications. Multidrug-resistant tuberculosis is tuberculosis that is resistant to at least isoniazid and rifampin (Rifadin®), two of the main drugs used to treat the disease. Bedaquiline is reserved for use in people who do not have other treatment options. 
 
(Click What Is Bedaquiline Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any medicine, bedaquiline can cause side effects. However, not everyone who uses the drug will experience problems. Most people tolerate it quite well.
 
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
 
Common side effects of bedaquiline include but are not limited to:
   
(Click Bedaquiline Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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