Drugs Home > Ambrisentan and the Liver

Ambrisentan (Letairis®) is a prescription medicine used to treat pulmonary arterial hypertension (PAH) in adults. Although this can be an effective form of treatment, ambrisentan is not suitable or safe for some people.
There have been reports of medications like ambrisentan causing liver problems. Let your healthcare provider know right away if you develop any signs of liver problems during ambrisentan treatment, such as:
  • Nausea and vomiting
  • Fever
  • Upper-right abdominal (stomach) pain
  • Yellowing of the skin or whites of the eyes (jaundice)
  • Constant fatigue or tiredness.
(Click Precautions and Warnings With Ambrisentan for more info on the drug's safety concerns.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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