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What If I Take an Overdose of Adapalene?

Applying too much of this medication may cause skin redness, peeling, and discomfort. Taking this medication by mouth may cause symptoms of vitamin A toxicity.
If you or someone else may have taken too much (or taken this medication by mouth), seek immediate medical attention.
(Click Differin Overdose for more information.)

What Should I Do If I Miss a Dose?

If you forget to apply adapalene at bedtime, simply skip your missed dose and continue with your regular schedule.

How Does Adapalene Work?

Adapalene belongs to a group of medications known as retinoids, meaning it is chemically related to vitamin A. Some other well-known retinoids include Retin-A® and Accutane®.
Adapalene and other retinoids are thought to work by suppressing inflammation and slowing down the rapid growth of skin cells.

When and How to Use It

Some general considerations include the following:
  • Apply this medication once daily to the affected areas in the evening just before bedtime. Use only a thin layer.
  • Wash your face (and/or other affected areas, such as the back) with a mild, soap-free cleanser before applying adapalene.
  • Make sure to avoid the area around the eyes and lips.
  • Do not apply more than a small amount; using an excess of this medicine increases the risk of skin irritation without increasing effectiveness.
  • Avoid excessive sun exposure, as you will burn more easily.
  • For the medication to work properly, it must be used as prescribed.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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