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Precautions and Warnings With Loteprednol

With loteprednol, there are many precautions to be aware of, including warnings relating to possible side effects and who should avoid the drug. For example, this prescription eye medication could increase the risk of glaucoma and may not be safe for women who are pregnant or breastfeeding. To help minimize risks, tell your doctor about any medical conditions you have before using this drug.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using loteprednol etabonate (Alrex®, Lotemax®) if you have:
  • An eye infection (including inactive eye infections, such as those that can happen with herpes)
  • Glaucoma
  • Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Loteprednol Warnings and Precautions

Some warnings and precautions to be aware of prior to using these eye medications include the following:
  • Like other steroids, loteprednol can increase the risk of eye infections or reactivation of inactive infections (such as those that can occur with herpes). If you have an eye infection or a history of eye infections, check with your healthcare provider before using loteprednol. Also, be sure to seek medical attention if you develop an eye infection while using these eye medications.
  • Steroids (such as loteprednol) can cause perforation of the eye in people who already have a thin surface of the eye (usually due to other medical conditions).
  • As a steroid, loteprednol may worsen or even cause glaucoma. It is a good idea for your healthcare provider to make sure you do not have glaucoma before you start using loteprednol. If you use these eye medications for more than 10 days, your healthcare provider should check to make sure that they are not causing glaucoma.
  • To help prevent contamination of the drops, do not touch the tip of the dropper to any surface, including the surface of the eye.
  • If you wear contact lenses, you must remove them to use the drops. In order to prevent the lens from absorbing the preservative in the medication, make sure to wait 10 minutes after using the drops before reinserting the lens. Do not wear your contact lenses if your eye is still red.
  • It is unknown if loteprednol passes through breast milk in significant amounts. Therefore, if you are breastfeeding or plan to start breastfeeding, discuss this with your healthcare provider prior to using the drug (see Alrex and Breastfeeding and Lotemax and Breastfeeding).
  • Loteprednol is considered a pregnancy Category C medication. This means that it might be unsafe for use during pregnancy, although the full risks are not currently known (see Alrex and Pregnancy or Lotemax and Pregnancy).
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Loteprednol Drug Information

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