Drug Interactions With Loratadine

Drug interactions with loratadine can occur if it is combined with cimetidine, ketoconazole, or erythromycin. These interactions may affect the level of loratadine in your blood; however, studies indicate that most people will not have any problems as a result. Because it's possible that not all drug interactions with loratadine are currently known, tell your healthcare provider about all medicines you currently take before taking loratadine.

Drug Interactions With Loratadine: An Overview

Loratadine (Claritin®) can potentially interact with a few other medications. Some of the medicines that may lead to drug interactions with loratadine include:
 

Interactions With Loratadine Explained

The following sections explain in detail the potentially negative interactions that can occur when loratadine is combined with any of the drugs listed above.
 
Cimetidine
Cimetidine may increase the level of loratadine in the blood, although studies suggest that this interaction is unlikely to cause any problems. However, you may want to consult with your healthcare provider, especially if you notice any increase in side effects of loratadine.
 
Erythromycin
Taking loratadine with erythromycin may change the way your body handles loratadine, possibly increasing the level of loratadine in your blood. However, this interaction seems unlikely to cause problems for most people.
 
Ketoconazole
Combining Nizoral with loratadine may increase the level of loratadine in your blood, although studies have not shown this to be a problem for most people.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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