Drug Interactions With Loratadine and Pseudoephedrine Sulfate

Certain medications can cause drug interactions with loratadine and pseudoephedrine sulfate, including erythromycin, cimetidine, and blood pressure medicines. While some interactions may increase the level of loratadine and pseudoephedrine sulfate in your blood, others can cause potentially serious complications, such as an irregular heart rhythm. To reduce the risk of drug interactions with loratadine and pseudoephedrine sulfate, tell your healthcare provider about all medications you are taking.

Loratadine and Pseudoephedrine for Allergies

Drug Interactions With Loratadine and Pseudoephedrine Sulfate: An Overview

Loratadine and pseudoephedrine sulfate (Claritin-D^®) can potentially interact with a few other medications. Some of the medicines that may lead to loratadine and pseudoephedrine sulfate drug interactions include:

Blood pressure medications
Cimetidine (Tagamet^®)
Digoxin (Digitek^®, Lanoxin^®)
Erythromycin (Ery-Tab^®)
Ketoconazole (Nizoral^®)
Monoamine oxidase inhibitors (MAOIs), such as:

Isocarboxazid (Marplan^®)
Phenelzine (Nardil^®)
Rasagiline (Azilect^®)
Selegiline (Eldepryl^®, Emsam^®, Zelapar^®)
Tranylcypromine (Parnate^®).

More Information on Loratadine and Pseudoephedrine Sulfate Interactions

The following sections explain in detail the potentially negative interactions that can occur when loratadine and pseudoephedrine sulfate is combined with any of the drugs listed above.

(Drug Interactions With Loratadine and Pseudoephedrine Sulfate Continued: Page 2)