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What Is Lomustine Used For?

Can Children Use It?

Lomustine is approved for use in children. It is important to note, however, that pulmonary fibrosis (a condition associated with scarring, stiffening, and thickening of the lungs) has been reported in people who were treated with medications similar to lomustine (that is, other nitrosourea medications) as children.
 
The lung damage associated with lomustine has been reported to occur as long as 17 years after treatment. It has also been reported to cause death. Talk to your child's healthcare provider about the risks and benefits of using this medicine in children.
 

Is It Safe for Older Adults to Use Lomustine?

Older adults can use lomustine. However, there were not enough people aged 65 and older in clinical trials to determine if older adults respond differently to the medicine than younger age groups.
 
Lomustine is removed from the body by the kidneys. Because older adults are more likely to have reduced kidney function, they may need to be monitored closely and may require lower doses of this medication.
 

What About Off-Label Uses?

On occasion, your healthcare provider may recommend this medication for treating something other than the conditions discussed in this article. This is called an "off-label" use. For example, lomustine may be used off-label to treat other types of cancer, such as:
 
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Lomustine Drug Information

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