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Lomustine

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
 
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Kidney disease, such as kidney failure (renal failure)
  • Lung disease
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
 
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Lomustine to learn more, including information on who should not take the drug.)
 

How Does It Work?

As previously mentioned, lomustine belongs to a group of drugs called alkylating agents. In general, alkylating agents transfer a piece of their structure, called an alkyl group, to DNA. This causes the strands of DNA to bond to each other and become linked (known as "cross-linking"). The linked strands cannot uncoil and separate, which is necessary for the DNA to replicate. Because DNA replication is essential for cells to grow and multiply, alkylating medications like lomustine prevent cell growth and multiplication.
 
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Lomustine Drug Information

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