High Triglycerides
High levels of
triglycerides (the fat-like substances in the body) in the blood can have many negative effects on the body as well. They can accumulate on the walls of arteries, which decreases the blood flow and oxygen supply to the heart, brain, and other parts of your body. Hypertriglyceridemia can also increase a person's risk for developing
heart disease,
angina, a
heart attack, and
stroke.
Very high levels of this fat-like substance can produce a condition known as
pancreatitis (inflammation of the
pancreas). Pancreatitis can be painful and sometimes causes serious health problems.
Lofibra has been licensed for the treatment of
high triglycerides in addition to diet and exercise. It works by increasing the breakdown and removal of these fat-like substances so that there are less in the body.
Lofibra can actually cause an increase in
LDL cholesterol for people with very high levels of triglycerides (greater than 350 mg/dL). Therefore, Lofibra should be used with extreme caution or not at all in people with this condition who also have high levels of LDL cholesterol.
Lofibra as One Part of Treatment
Lowering triglyceride and
cholesterol levels generally begins with lifestyle modifications. This includes a diet low in cholesterol and saturated fats, limited alcohol use, weight loss, and exercise. If lifestyle changes alone do not lower triglyceride or
cholesterol levels enough, certain medications, such as Lofibra, may be necessary.
Since Lofibra can lower both LDL cholesterol and triglyceride levels (along with lowering total cholesterol and increasing
HDL), a person can decrease his or her risk of developing certain health problems in the future by using this drug.
Lofibra has not been approved for use in children
Previous
