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Leuprolide Dosage

The amount of leuprolide you are prescribed will depend on several factors, such as the condition being treated and how you respond to leuprolide. Dosages may be given once a day, once a month, once every three months, or once every six months. Some products are injected just below the skin, while another is injected into a muscle.

An Introduction to Your Dose of Leuprolide

The dosage of leuprolide (Eligard®, Lupron®, Lupron Depot®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • The particular leuprolide product you are using
  • The reasons you are using the medicine
  • How you respond to it
  • Your weight (in children).
As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.

Leuprolide Dosing for Prostate Cancer

The standard dose of leuprolide for advanced prostate cancer depends on how frequently the doses are given. Normally, one of the following is prescribed:
  • Leuprolide 1 mg once a day (Lupron)
  • Leuprolide 7.5 mg once a month (Eligard or Lupron Depot)
  • Leuprolide 22.5 mg every three months (Eligard or Lupron Depot)
  • Leuprolide 30 mg every four months (Eligard or Lupron Depot)
  • Leuprolide 45 mg every six months (Eligard or Lupron Depot).
Lupron and Eligard are injected subcutaneously (just under the skin). Lupron Depot is injected intramuscularly (into a muscle).

Leuprolide Dosing for Central Precocious Puberty

The standard dosage of leuprolide for central precocious puberty (early puberty in children) is based on the child's body weight. The actual dose used will vary from child to child and will depend on the leuprolide product used.
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