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Leuprolide and Breastfeeding

Because no research has been done on breastfeeding and leuprolide (Eligard, Lupron, Lupron Depot), it is unclear if the drug passes through breast milk or if it would cause any problems in a nursing child. However, the medication does affect estrogen levels within the body, and this could interfere with the production of breast milk.

Is Taking Leuprolide While Breastfeeding Safe?

Leuprolide (Eligard®, Lupron®, Lupron Depot®) is an injectable hormone medication. It is available by prescription only and is used to manage symptoms of endometriosis and uterine fibroids in women. Leuprolide is also used in men with advanced prostate cancer and in children who are starting to undergo puberty too early.
It is unknown if leuprolide passes through breast milk. In general, this medication is not recommended for use in breastfeeding women.

More Information on Breastfeeding and Leuprolide

No research has been done to see if leuprolide passes through breast milk. It is also unknown if leuprolide affects breast milk supply or if it would harm a nursing child. While this lack of information is certainly frustrating, it is important to understand that medications are rarely studied in breastfeeding women, as this would usually expose an infant, who will not directly benefit from the medication, to possible risks.
Leuprolide is not active when taken orally, much like insulin used in diabetes. Therefore, it probably wouldn't cause problems if consumed by a nursing infant through breast milk. However, because leuprolide affects estrogen levels, it could potentially affect production of breast milk. In addition, because it has not been studied in breastfeeding women, all potential problems cannot be ruled out.
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Leuprolide Acetate Drug Information

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