People who experience moderate to severe pain may benefit from ketorolac tromethamine (Toradol®). This prescription medication is approved for the short-term relief of pain caused by a procedure, kidney stones, back pain, or cancer pain.
It is thought that blocking the effects of prostaglandins is what makes ketorolac useful for reducing pain. In clinical studies, ketorolac was as effective as lower doses of narcotics at treating pain. When it was combined with narcotic pain medicines (such as morphine), it decreased the amount of narcotics needed. Also, pain relief was significantly better in those receiving ketorolac and morphine compared to those receiving morphine alone.
Pain relief usually begins about 30 minutes after the dosage is received. The maximum effect of ketorolac tromethamine occurs within two to three hours and lasts, on average, for four to six hours. Possible side effects of the medication include nausea, drowsiness, and headaches.
Ketorolac is available in the form of an injection or as tablets. The injections are available in several strengths, including 15 mg per mL vial, 30 mg per mL vial, and 60 mg per 2-mL vial. The tablets are available in one strength -- ketorolac 10 mg.
(Click Ketorolac for more information on how ketorolac tromethamine works, potential side effects of the medication, and some general precautions to be aware of before starting treatment.)