Several different types of blood clots can be treated with Jantoven. Uses of the medication include the prevention and treatment of blood clots in the veins or lungs and in people with atrial fibrillation or artificial heart valves. Healthcare providers may also occasionally recommend off-label uses, such as preventing recurrent transient ischemic attacks ("mini strokes").
Jantoven® (warfarin sodium) is a prescription medication used to prevent and treat blood clots. Specifically, Jantoven is approved for the following uses:
- Prevention and treatment of blood clots or related problems (such as strokes) in people with atrial fibrillation or artificial heart valves
- Reduction of the risk of death, repeat heart attacks, blood clots, or strokes after a heart attack
- Prevention and treatment of blood clots in the veins (such as with deep vein thrombosis)
- Prevention and treatment of blood clots in the lungs (pulmonary embolism).
While Jantoven can be a life-saving medication, it has both disadvantages and advantages. Advantages include low cost and painless oral dosing. Disadvantages include the need for frequent monitoring (using blood tests), numerous food and drug interactions, and a narrow range for both safety and effectiveness (taking too little increases the risk of blood clots, while taking too much increases the risk of dangerous internal bleeding). Jantoven is difficult to dose, and the cost of monitoring must also be taken into account.
Furthermore, Jantoven is slow to start working. In fact, when a person first starts taking it, he or she actually may be at an increased risk for clots, since Jantoven first decreases certain anticoagulant proteins in the body before it starts working to prevent clots. As a result, in many cases, people will need to be on heparin (or some other form of injectable or IV anticoagulant) for a few days until Jantoven starts working.