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Drug Interactions With Ivacaftor

Digoxin, cyclosporine, and certain other drugs may cause potentially serious interactions when combined with ivacaftor. Some of these reactions can increase the risk for side effects or decrease the effectiveness of the medicines. Your healthcare provider may need to monitor you more closely if you combine ivacaftor with other products, and adjust any dosages if necessary.

An Overview of Ivacaftor Interactions

Ivacaftor (Kalydeco™) can potentially interact with a number of other medications. Some of the products that may lead to drug reactions with ivacaftor include but are not limited to:
 
 
 
  • CYP 3A4 inhibitor medications, such as:
 
 
 

Ivacaftor Drug Information

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