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Side Effects of Intravenous Acetaminophen

Although most people do not experience problems while receiving intravenous acetaminophen, side effects are possible. Some of the common reactions to this drug include nausea, vomiting, and headaches. Serious problems have also been known to occur with this medication. Contact your healthcare provider immediately if you notice difficulty breathing, yellowing of the whites of the eyes or skin, or other potentially dangerous side effects.

An Introduction to Side Effects of Intravenous Acetaminophen

As with any medicine, intravenous acetaminophen (Ofirmev™) can cause side effects. However, not everyone who receives the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with this drug. Your healthcare provider can discuss a more complete list with you.)

Intravenous Acetaminophen Side Effects to Report

Some side effects with intravenous acetaminophen are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of liver damage, such as:
    • Dark urine
    • Yellowing of the whites of the eyes or skin (jaundice)
    • Abdominal (stomach) pain, especially near the liver (the upper right part of the abdomen)
  • Signs of a serious allergic reaction, such as:
    • An unexplained rash
    • Itching
    • Hives
    • Redness of the face
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
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IV Acetaminophen Information

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