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Drug Interactions With Intravenous Acetaminophen

Isoniazid
Combining intravenous acetaminophen with isoniazid may increase your risk of liver damage. Talk to your healthcare provider before using these medications together.
 
Many Cough, Cold, Pain, and Allergy Products
Many of these types of medications contain acetaminophen, the active ingredient of intravenous acetaminophen. Your healthcare provider will need to take this into account when calculating your intravenous acetaminophen dosage. Make sure your healthcare provider knows if you have taken any acetaminophen products recently.
 
Oxycodone and Acetaminophen
If you take any other acetaminophen products, such as oxycodone and acetaminophen, your healthcare provider will need to take this into account when calculating your intravenous acetaminophen dosage. Make sure your healthcare provider knows if you have taken any acetaminophen products recently.
 
Propoxyphene and Acetaminophen
If you take any other acetaminophen products, such as propoxyphene and acetaminophen, your healthcare provider will need to take this into account when calculating your intravenous acetaminophen dosage. Make sure your healthcare provider knows if you have taken any acetaminophen products recently.
 
Tramadol and Acetaminophen
If you take any other acetaminophen products, such as tramadol and acetaminophen, your healthcare provider will need to take this into account when calculating your intravenous acetaminophen dosage. Make sure your healthcare provider knows if you have taken any acetaminophen products recently.
 
Warfarin
Combining warfarin with intravenous acetaminophen may increase your risk for bleeding. However, this risk is much less than many other pain relievers (such as aspirin). If you suddenly and drastically change your intravenous acetaminophen intake, contact your healthcare provider, as you may need to be monitored more closely.
 
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IV Acetaminophen Information

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