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What Is Icatibant Used For?

If you have a rare genetic condition called hereditary angioedema (HAE), you may receive icatibant. It is used for treating sudden HAE attacks, which cause swelling under the skin in various areas of the body. Icatibant is used at the first sign of an HAE attack; it helps relieve symptoms and prevent them from becoming worse. This drug is approved for use in adults only.

An Overview of Uses for Icatibant

Icatibant (Firazyr®) is a prescription injectable medication approved to treat sudden attacks of swelling associated with hereditary angioedema (HAE). It belongs to a class of medicines known as bradykinin inhibitors.
 
Hereditary angioedema is a rare genetic condition that is usually passed down through families. People with this condition have recurrent episodes of angioedema, or sudden swelling under the skin. The swelling can occur in any area of the body, but commonly affects the hands, feet, face, intestinal tract, and larynx (throat).
 
Episodes of swelling normally begin in childhood, with symptoms worsening around the time of puberty. The frequency of attacks can vary from person to person. While some people experience attacks weekly, others may only have them once a year, or even less frequently.
 
Attacks usually resolve on their own after two to five days, but can be associated with significant symptoms during that time. Swelling of the hands and feet can impair a person’s ability to go about their daily activities. Episodes affecting the intestinal tract can cause significant pain, diarrhea, nausea, and diarrhea. Throat swelling is particularly dangerous, as it can block the airway and become life-threatening.
 
Icatibant can be used at the first sign of symptoms to treat the HAE episode and prevent it from progressing. Icatibant is not a cure for HAE, and is not approved to prevent attacks from occurring.
 

Icatibant Drug Information

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