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Drug Interactions

Gemfibrozil may interact with several different medications (see Drug Interactions With Gemfibrozil for more information).

What Should I Tell My Healthcare Provider?

Prior to taking gemfibrozil, tell your healthcare provider if you have:
  • Gallbladder disease or gallstones
  • Kidney disease or kidney failure
  • Liver disease or liver failure
  • Diabetes
  • Heart disease
  • Any allergies, including allergies to medications, foods, dyes, or preservatives.
It is also important to let your healthcare provider know if you are:
  • Pregnant or planning on becoming pregnant (see Lopid and Pregnancy)
  • Breastfeeding 
  • A frequent user of alcoholic beverages.
Tell your healthcare provider about all the medicines you may currently be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Gemfibrozil for more information, including information on who should not take the drug.)

Alternatives to Gemfibrozil

Lowering triglyceride and cholesterol levels should begin with lifestyle modifications. This includes exercise, weight loss, limited alcohol use, and a diet low in cholesterol and saturated fats. If lifestyle changes alone do not lower triglyceride or cholesterol to desirable levels, certain medications may be necessary.
In general, cholesterol treatment is aimed at lowering LDL cholesterol levels enough to reduce the risk of developing complications associated with high cholesterol (see Effects of High Cholesterol). If you are at a higher risk, you will have a lower LDL goal.
(Click High Cholesterol Risk to determine your cholesterol risk and find out what your LDL cholesterol level should be.)
For most people, gemfibrozil is quite effective and it is also generally well tolerated. But side effects can occur and people may wish to consider a substitute. These substitutes could include other fibrates, statins, or other cholesterol medicines.
(Click Lopid Alternatives to learn more about substitutes for gemfibrozil.)
10 Foods That Lower Cholesterol

Gemfibrozil Information

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