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Precautions and Warnings With Gablofen

If you have epilepsy or any type of infection, let your healthcare provider know before receiving Gablofen. Your healthcare provider will also need to know whether you are pregnant or breastfeeding. Other precautions and warnings involve being aware that Gablofen could make certain mental illnesses worse. Gablofen can also interact with certain medications.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to receiving Gablofen® (baclofen) if you have:
  • Epilepsy or a history of seizures
  • Mental illness of any kind
  • Any sort of infection
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Gablofen Precautions and Warnings

Some warnings and precautions to be aware of prior to receiving this medication include the following:
  • Gablofen is only given intrathecally (into the intrathecal space around the spinal cord). It cannot be given intravenously (by IV), subcutaneously (under the skin), intramuscularly (into a muscle), or by an epidural.
  • Stopping Gablofen too quickly can lead to dangerous withdrawal symptoms (see Baclofen Withdrawal). Carefully adhere to your refilling schedule to avoid running out.
  • Gablofen usually causes drowsiness. It can also cause dizziness or confusion. Make sure you know exactly how this medicine affects you before driving or operating heavy machinery.
  • Gablofen may increase the risk for ovarian cysts.
  • You must not have any sort of infection during the initial test phase, as an infection can interfere with your response to the drug. You should not have an infection when having the pump implanted either, due to the risk of surgical complications.
  • There have been cases of masses (lumps) forming at the tip of the intrathecal catheter in people using intrathecal baclofen products, including Gablofen. However, most of these cases occurred when baclofen was mixed with other medications.
  • Your healthcare provider should take extreme precautions when adjusting your dosage or refilling the pump in order to avoid an accidental overdose. Your healthcare provider must be prepared in case of an emergency situation.
  • There have been reports of Gablofen making various mental illnesses worse. Your healthcare provider should monitor you for any signs of such problems.
  • Gablofen is a pregnancy Category C medication. This means it might not be safe for use during pregnancy, although the full risks are currently unknown. Talk to your healthcare provider about the risks and benefits of using Gablofen during pregnancy (see Baclofen and Pregnancy).
  • Baclofen, the active ingredient in Gablofen, passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to receiving the drug (see Baclofen and Breastfeeding).
Know the Signs - Concussion Safety

Gablofen Medication Information

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