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Drug Interactions With Gablofen

Your healthcare provider needs to know about all other medications you are taking, including cold medicines or products that contain alcohol, before you can receive Gablofen. Drugs that cause drowsiness or sedation can increase the risk for severe drowsiness, confusion, dizziness, or other interactions when combined with Gablofen. Do not use these products without first talking to your healthcare provider.

An Overview of Gablofen Interactions

Gablofen® (baclofen) may react with several other medications. Some of the drugs that may interact with Gablofen include but are not limited to:
  • Alcoholic beverages, or other products that contain alcohol
  • Antidepressant medications
  • Antihistamines, including many nonprescription cold, cough, allergy, motion sickness, and sleep medications
  • Antipsychotics, such as:
  • Barbiturates, such as:


    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
  • Benzodiazepine sedatives, such as:
  • Muscle relaxants, such as:
  • Monoamine oxidase inhibitors (MAOIs), such as:
Know the Signs - Concussion Safety

Gablofen Medication Information

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