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Gabapentin Enacarbil Side Effects

Common Side Effects

Gabapentin enacarbil has been studied thoroughly in clinical trials. In these studies, one group of people received gabapentin enacarbil, while another group was given a placebo (a "sugar pill" with no active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In clinical trials, the most common side effect of gabapentin enacarbil 600 mg once daily (the standard recommended dosage) included:
  • Drowsiness -- in up to 20 percent of people
  • Dizziness -- up to 17 percent
  • Headache -- up to 12 percent
  • Nausea -- up to 8 percent
  • Fatigue -- up to 6 percent
  • Swelling and water retention in the extremities (hands, ankles, and feet) -- up to 6 percent 
  • Irritability -- up to 4 percent.
Other common gabapentin enacarbil side effects, occurring in 1 to 3 percent of people, included but were not limited to:
  • Dry mouth
  • Gas
  • Feeling "drunk"
  • Increased appetite
  • A spinning sensation (vertigo).
This data includes information about the side effects reported at the recommended gabapentin enacarbil dosages. Taking higher dosages increases the risks for many of these side effects.

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking gabapentin enacarbil or if you develop something that "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
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Gabapentin Enacarbil Drug Information

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