Drugs Channel
Topics & Medications
Quicklinks
Related Channels

What Is Fondaparinux Used For?

How Does Fondaparinux Work?

Fondaparinux works by inhibiting a specific clotting factor known as factor Xa. It is more selective than heparin (including both unfractionated heparin and low molecular weight heparins), which inhibits other clotting factors as well. Notably, this medication does not affect blood platelets. It is not a heparin medication.
 
Like other "blood thinners," fondaparinux does not break down clots. Instead, it slows down clot formation, giving the body a chance to break down the clots naturally.
 

Can Children Use Fondaparinux?

Fondaparinux is not approved for use in children. This does not mean that children absolutely cannot take fondaparinux; it just means that this medication (like most medications) has not been adequately studied in children. Talk with your child's healthcare provider about the particular benefits and risks of using fondaparinux in children.
 
It is known that small adults (who weigh less than 110 pounds) are at a higher risk for dangerous bleeding, compared to larger adults. This suggests that dangerous bleeding could be a problem when using fondaparinux in children.
 

Is Fondaparinux Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend fondaparinux for something other than the uses discussed in this article. Some possible off-label uses of fondaparinux include:
 
  • Preventing death or future heart attacks after certain "cardiac events" (such as heart attacks)
  • Preventing blood clots in people who cannot take heparin medications due to a history of "heparin-induced thrombocytopenia" (HIT)
  • "Bridge therapy" in people who must temporarily stop taking warfarin (Coumadin®, Jantoven®)
  • Long-term management of clotting disorders in people who cannot take warfarin
  • Preventing DVT after moderate-risk general surgeries
  • Preventing DVT after gynecological surgery
  • Preventing DVT in people with cancer
  • Managing clotting disorders in pregnant women or preventing recurring pregnancy loss, particularly in women who cannot take heparin medications (see Arixtra and Pregnancy).
     
Fondaparinux may be approved in other countries for these uses, but in the United States they are unapproved, "off-label" uses.
 
6 Things That Worsen or Cause ED

Fondaparinux Drug Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.