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Drug Interactions With Fondaparinux

Drug Interactions With Fondaparinux Explained

The following sections explain in detail the potential problems that can occur when fondaparinux is combined with any of the drugs listed above.
 
Dasatinib
Combining fondaparinux with dasatinib may increase the risk of bleeding, including dangerous internal bleeding. If you must take these medications together, your healthcare provider should monitor you more closely than usual.
 
Drotrecogin Alfa
Combining fondaparinux with drotrecogin alfa may increase the risk of bleeding, including dangerous internal bleeding. If you must take these medications together, your healthcare provider should monitor you more closely than usual. This appears to be more of a problem with the higher doses of fondaparinux used to treat blood clots, rather than the lower dosages used to prevent them.
 
Ibritumomab
Combining fondaparinux with ibritumomab may increase the risk of bleeding, including dangerous internal bleeding. If you must take these medications together, your healthcare provider should monitor you more closely than usual.
 
Pentosan Polysulfate Sodium
Combining fondaparinux with pentosan polysulfate sodium may increase the risk of bleeding, including dangerous internal bleeding. If you must take these medications together, your healthcare provider should monitor you more closely than usual.
 
Tositumomab
Combining fondaparinux with tositumomab may increase the risk of bleeding, including dangerous internal bleeding. If you must take these medications together, your healthcare provider should monitor you more closely than usual.
 
Other Medications That "Thin" the Blood
Other medications that have anticoagulant, antiplatelet, or thrombolytic effects may increase the risk of bleeding with fondaparinux. Always check with your healthcare provider before combining fondaparinux with any such medications. Sometimes, these medications (especially thrombolytics, aspirin, or warfarin) are intentionally combined with fondaparinux.
 
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Fondaparinux Drug Information

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