Drug Interactions With Fluvastatin
There are a number of medications that may cause fluvastatin drug interactions. When fluvastatin is taken with medicines such as fibrates, cholestyramine, or ranitidine, your body may metabolize both drugs differently than intended. This can result in altered levels of medication in the blood and cause a greater risk of developing serious muscle problems.
Fluvastatin Interactions: An Overview
Fluvastatin (Lescol®) can potentially interact with several other medications. Some of the medications that can lead to drug interactions with fluvastatin include:
- Cholestyramine (Questran®, LoCholest®, Prevalite®)
- Cimetidine (Tagamet®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Diclofenac (Cataflam®, Voltaren®)
- Digoxin (Digitek®, Lanoxicaps®, Lanoxin®)
- Erythromycin (Ery-Tab®)
- Fibrates, such as:
- Fluconazole (Diflucan®)
- Glyburide (DiaBeta®, Glynase®, Micronase®)
- Ketoconazole (Nizoral®)
- Niacin (nicotinic acid, Niacor®, Nicolar®)
- Omeprazole (Prilosec®, Prilosec OTC®) or omeprazole/sodium bicarbonate (Zegerid®, Zegerid OTC™)
- Phenytoin (Dilantin®, Phenytek®)
- Ranitidine (Zantac®)
- Rifampin (Rifadin®)
- Spironolactone (Aldactone®, Aldactazide®)
- Warfarin (Coumadin®, Jantoven®).
Some of these drug interactions may increase your risk for developing serious muscle problems (see Lescol and Muscle Pain). If you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied with a fever or if you feel ill, it is important to contact your healthcare provider right away.