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Fluticasone Propionate Ointment Side Effects

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Fluticasone propionate ointment has been studied thoroughly in clinical trials. In these studies, one group of people used the medicated ointment, while another group was given a placebo (an ointment with no active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In clinical trials, there were no "common" side effects (that is, none of the side effects occurred in more than 1 percent of people). The most commonly reported reactions, which were, in fact, not common at all, included:
- Itching
- Burning
- Increased sweating
- Redness
- Hives
- Irritation
- Lightheadedness.
In general, side effects are more common when a dressing (such as a bandage) is used to cover the medication. Do not use a dressing or bandage when using fluticasone propionate ointment.
Using steroids like fluticasone propionate ointment for a long time can cause a different set of side effects. These are most likely to be seen in people that use fluticasone propionate ointment over a large area of the body for a long time, and might include:
- Weight gain
- Bulging eyes
- Fluid retention
- Osteoporosis
- Loss of muscle
- Fat deposits on the face and back, causing a round face and a fatty hump on the back of the neck
- Diabetes
- Cataracts
- Stunted growth (in children).
Keep in mind that such side effects are much more common with systemic steroids, which are taken by mouth or injection, and are probably quite rare with fluticasone propionate ointment.
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD



