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Drug Interactions With Fluticasone Furoate

Certain medicines may cause drug interactions with fluticasone furoate, including protease inhibitors and some antifungals or antibiotics. These medicines can increase the level of fluticasone furoate in your blood, which could lead to potentially serious side effects. Make sure your healthcare provider knows about all other drugs you are taking to help prevent fluticasone furoate interactions.

Drug Interactions With Fluticasone Furoate: An Overview

Fluticasone furoate (Veramyst™) can potentially interact with other medications. Some of these medicines that may lead to fluticasone furoate drug interactions include:
  • Certain antibiotics or antifungals, including:
o Erythromycin (Ery-Tab®)
o Isoniazid (Nydrazid®)
o Itraconazole (Sporanox®)
o Ketoconazole (Nizoral®)
o Telithromycin (Ketek®)
  • Protease inhibitors, such as:

Fluticasone Furoate Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when fluticasone furoate is combined with any of the drugs listed above.
Certain Antibiotics and Antifungals
Some antibiotics and antifungals can increase the level of fluticasone furoate in your blood, perhaps increasing your risk of fluticasone furoate side effects. In particular, too much fluticasone furoate in your blood can suppress your body's ability to produce natural steroids, which can cause serious consequences. This interaction is most likely to be a problem for people taking both antibiotics and antifungals on a long-term basis. Your healthcare provider may need to decrease your fluticasone furoate dosage.
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