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Drug Interactions With Fluconazole

Tacrolimus
Fluconazole may increase the level of tacrolimus in the blood, and taking these medications together may increase the risk of kidney damage. Check with your healthcare provider before combining these medications.
 
Tetrabenazine
Combining tetrabenazine with fluconazole may increase the risk of a dangerous irregular heart rhythm (arrhythmia). It is generally recommended to avoid combining these medications.
 
Theophylline
Fluconazole increases the level of theophylline in the blood. If you take these medications, your healthcare provider should monitor your theophylline levels and adjust your dosage as necessary.
 
Thioridazine
Combining thioridazine with fluconazole may increase the risk of a dangerous irregular heart rhythm (arrhythmia). In general, these medicines should not be taken together.
 
Tofacitinib
Fluconazole can increase the level of tofacitinib in the bloodstream, increasing the risk for side effects. If you must take these medications together, your healthcare provider may need to lower your tofacitinib dosage to account for this interaction.
 
Voriconazole
Fluconazole can increase the level of voriconazole in the bloodstream, increasing the risk for side effects. These medications should not be taken together.
  
Warfarin
Fluconazole may increase the risk of bleeding due to warfarin. Your healthcare provider should monitor you closely and adjust your warfarin dosage as necessary if you are taking both of these drugs.
 

Final Thoughts on Fluconazole Drug Interactions

It is possible that not all interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with fluconazole that may apply to you.
 
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Fluconazole Drug Information

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