Fexofenadine and Pseudoephedrine

Fexofenadine and pseudoephedrine is a combination medicine that is used for the treatment of common hay fever symptoms. By blocking the effects of histamine and decreasing the swelling in the nasal passages, the medication is effective in relieving symptoms such as sneezing; nasal congestion; runny nose; and itchy, watery, or red eyes. The prescription drug comes in tablet form and is available in several strengths, including fexofenadine 60 mg and pseudoephedrine hydrochloride 120 mg, as well as fexofenadine 180 mg and pseudoephedrine hydrochloride 240 mg.

 

What Is Fexofenadine and Pseudoephedrine?

Fexofenadine and pseudoephedrine (Allegra-D®) is a prescription medication that is used to treat seasonal allergies (hay fever).
 
Fexofenadine and pseudoephedrine is manufactured by Sanofi-Aventis Pharmaceuticals.
 
(Click What Is Fexofenadine and Pseudoephedrine Used For? for more information on its uses.)
 

How Does Fexofenadine and Pseudoephedrine Work?

When you come in contact with something you're allergic to, a chain reaction begins inside your body. During this chain reaction, special cells release powerful chemicals. Some of these chemicals can trigger swelling of the nasal passages, leading to nasal congestion (a "stuffy nose"). Other chemicals, such as histamine, can cause sneezing, itching, and irritation.
 
Fexofenadine and pseudoephedrine is a combination medication. Fexofenadine (Allegra®) is part of a class of drugs called antihistamines. Allegra blocks the effects of histamine (hence its classification as an antihistamine). This leads to the relief of allergy symptoms -- except for nasal congestion. Pseudoephedrine (the most common brand name being Sudafed®) is a decongestant. It works by decreasing the swelling in the nasal passages, which improves the nasal congestion.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;