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Side Effects of Fentanyl Lozenge

Notify your healthcare provider if you are using fentanyl lozenges and develop serious side effects, such as seizures, hallucinations, or severe constipation. In most cases, however, people tolerate the medication well, and any side effects that occur are typically easy to treat. The most common side effects include nausea, drowsiness, and dizziness. Other, less common side effects may include fever, dry mouth, and heartburn.

An Introduction to Side Effects of Fentanyl Lozenges

As with any medicine, the fentanyl lozenge (Actiq®) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with fentanyl lozenges. Your healthcare provider can discuss a more complete list with you.)

Serious Fentanyl Lozenge Side Effects

Some fentanyl lozenge side effects are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • The urge to use more fentanyl lozenges than prescribed or for a non-medical purpose (see Actiq Abuse)
  • Any difficulty breathing, including reduced, shallow, slow, or irregular breathing
  • A slow heart rate (bradycardia)
  • Severe drowsiness
  • Cold and clammy skin
  • Feeling faint, extremely dizzy, or confused
  • Seizures
  • Severe constipation
  • Unusual changes in behavior or mood (including depression, hostility, agitation, or anxiety)
  • Hallucinations (seeing or hearing things that are not really there)
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
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Fentanyl Lozenge Drug Information

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