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Drug Interactions With Fentanyl Buccal Soluble Film

Drug Interactions With Fentanyl Buccal Soluble Film Explained

The following sections explain in detail the potentially negative interactions that can occur when fentanyl buccal soluble film is combined with any of the drugs listed above.
 
Alcohol
Consuming alcohol while using fentanyl buccal soluble film could increase your risk for serious side effects, including extreme drowsiness, confusion, or breathing problems. You should avoid alcohol while using this medication.
 
Alvimopan
Fentanyl buccal soluble film may increase the risk for serious alvimopan side effects. Do not take alvimopan if you have used fentanyl buccal soluble film in the past seven days.
 
Amphetamines
Combining amphetamines with fentanyl buccal soluble film may increase the pain-relieving effects of fentanyl. Your healthcare provider may choose to monitor your response if you use these medications together. You might need a lower fentanyl buccal soluble film dosage.
 
Beta Blockers
Using fentanyl buccal soluble film with a beta blocker may decrease your heart rate and blood pressure to potentially unsafe levels. If you must use these medications together, your healthcare provider may need to monitor your blood pressure and heart rate more closely.
 
Calcium Channel Blockers
Using fentanyl buccal soluble film with certain calcium channel blockers may cause your heart rate and blood pressure to decrease to potentially unsafe levels. Your healthcare provider may need to monitor your blood pressure and heart rate more closely if you use these medications together.
 
CYP 3A4 Inducer Medications
The body breaks down fentanyl buccal soluble film using enzymes in the liver known as CYP 3A4 enzymes. Medications known as CYP 3A4 inducers can increase the activity of these enzymes. Combining fentanyl buccal soluble film with one of these drugs may decrease the level of fentanyl in your body, making it less effective. Your healthcare provider may need to monitor you more closely to make sure your pain is adequately controlled if you use these medications together.
Alternative Therapies for Pain Management

Fentanyl Buccal Soluble Film Information

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