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Ezetimibe/Simvastatin Dosage

The standard recommended ezetimibe/simvastatin dosage for most people with high cholesterol is 10/20 mg a day, taken with the evening meal. If you have not reached your cholesterol goals after several weeks, your healthcare provider may increase your dosage as needed. People with severe kidney disease may need to take a lower dose of the medication.

Ezetimibe/Simvastatin Dosing: An Introduction

The dose of ezetimibe/simvastatin (Vytorin®) your healthcare provider recommends will vary, depending on a number of factors, including:
 
As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.
 

Dosage of Ezetimibe/Simvastatin for High Cholesterol

The recommended starting ezetimibe/simvastatin dose for most people with high cholesterol is 10/20 mg a day, taken with the evening meal.
 
After several weeks, your healthcare provider will likely recommend that you return to recheck your cholesterol levels. If you have not reached your cholesterol goal at this time, your healthcare provider may choose to increase your dose of ezetimibe/simvastatin. The dosage can also be decreased if side effects of ezetimibe/simvastatin occur.
 
Some of the medications that interact with the simvastatin component in such a way as to require lower-than-usual ezetimibe/simvastatin dosages include:
 
 
(Click Drug Interactions With Ezetimibe/Simvastatin for more information.)
 
If you need to lower your cholesterol by only a small amount, or if you have severe kidney disease, a lower ezetimibe/simvastatin dosage may be recommended.
 
Due to the increased risk of serious muscle problems at higher dosages, the maximum recommended dosage of the simvastatin component of this medication is 40 mg per day. However, people who have already been taking 80 mg daily for a year or more with no muscle problems may continue to take that dosage.
  
The Dirty, Messy Part of BPH

Ezetimibe and Simvastatin Drug Information

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