Esomeprazole Drug Interactions

Mesalamine
Esomeprazole may interfere with the delayed-release mechanism of Apriso capsules, perhaps making Apriso less effective. This is not thought to be a problem with other mesalamine products. In general, these medications should not be taken together.
 
Some Protease Inhibitors
Esomeprazole may decrease the level of atazanavir or nelfinavir in the blood. It may increase the level of saquinavir in the blood. If you take a protease inhibitor, check with your healthcare provider before taking esomeprazole. In many situations, esomeprazole will not be recommended.
 
Warfarin
It is possible that esomeprazole could increase your risk of bleeding due to warfarin. Your doctor may choose to monitor your INR and prothrombin time more frequently, and adjust your warfarin dosage accordingly
 

Drug Interactions With Esomeprazole: Things to Remember

It is possible that not all drug interactions were discussed in this article. Therefore, you should talk with your healthcare provider about any specific drug interactions with esomeprazole that may apply to you.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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