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Esomeprazole Drug Interactions

Esomeprazole Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when esomeprazole is combined with any of the drugs listed above.
 
Certain Antifungal Medications
Combining esomeprazole with certain antifungals may decrease the effectiveness of the antifungal (due to decreased absorption) and may also increase the level of esomeprazole in the blood. Check with your healthcare provider before taking these medications together.
 
Cilostazol
Esomeprazole may increase the level of cilostazol in the blood. If you must take these two medications together, your healthcare provider should consider lowering your cilostazol dosage (to perhaps 50 mg twice daily).
 
Clopidogrel (Plavix)
Some research suggests that proton pump inhibitors (PPIs), like esomeprazole, may decrease the effectiveness of clopidogrel. This could potentially be a serious drug interaction. However, experts are still in disagreement about how significant this interaction really is and whether it affects all PPIs. Do not combine these medications without discussing the matter with your healthcare provider first.
   
Dasatinib
Esomeprazole may decrease the absorption of dasatinib, perhaps making it less effective. Your healthcare provider may recommend an alternative to esomeprazole while you are taking dasatinib.
 
Diazepam
When taking esomeprazole with diazepam, your body may metabolize the medicines differently than intended, although this potential interaction is not believed to be significant in most cases. You may wish to discuss this with your healthcare provider, prior to starting esomeprazole.

Esomeprazole Magnesium

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