Certain Antifungal Medications
Combining
esomeprazole with certain antifungals may decrease the effectiveness of the antifungal (due to decreased absorption) and may also increase the level of esomeprazole in the blood. Check with your healthcare provider before taking these medications together.
Dasatinib
Esomeprazole may decrease the absorption of dasatinib, perhaps making it less effective. Your healthcare provider may recommend an alternative to esomeprazole while you are taking dasatinib.
Diazepam
When taking esomeprazole with
diazepam, your body may metabolize the medicines differently than intended, although this potential interaction is not believed to be significant in most cases. You may wish to discuss this with your healthcare provider, prior to starting esomeprazole.
Digoxin
Esomeprazole may slightly increase the level of digoxin in the blood. Your healthcare provider may choose to monitor you more closely.
Erlotinib
Esomeprazole may decrease the absorption of erlotinib, perhaps making it less effective. Your healthcare provider may recommend an alternative to esomeprazole while you are taking erlotinib.
Iron
Esomeprazole may decrease the absorption of iron supplements and medications, since stomach acid is necessary for iron absorption. If you need to take iron for a medical reason (such as for anemia), your healthcare provider may recommend an alternative to esomeprazole.
Mesalamine
Esomeprazole may interfere with the delayed-release mechanism of
Apriso capsules, perhaps making Apriso less effective. This is not thought to be a problem with other
mesalamine products. In general, these medications should not be taken together.
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