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What Is Ecallantide Used For?

How Does This Medicine Work?

Ecallantide blocks the activity of a protein in the body called plasma kallikrein. In the body, plasma kallikrein converts a chemical known as kininogen into another chemical called bradykinin. Bradykinin causes veins your body to dilate, or widen.
 
During an HAE attack, too much bradykinin is made and your veins can leak fluid; this can cause swelling and pain. By blocking the activity of plasma kallikrein, less bradykinin is made; therefore, there is less swelling and pain.
 

Can Children Use It?

This medication is not approved for use in children younger than 12 years of age. This does not mean that children absolutely cannot use ecallantide; it just means that this medication has not been adequately studied in children younger than 12 years old. Talk with your child's healthcare provider about the particular benefits and risks of using ecallantide in children.
 

What About Off-Label Uses?

On occasion, a healthcare provider may recommend a medication for something other than its approved use. However, ecallantide currently does not have any well-accepted off-label uses.
 

Ecallantide Drug Information

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