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Ecallantide Dosage

When using ecallantide, the standard dosage is three injections given just under the skin of the abdomen (stomach), thigh, or upper arm. Additional injections can be given if the HAE attack continues; however, these additional injections must be given within 24 hours of the first dose.

An Introduction to Your Dosage of Ecallantide

There is only one standard dosage for ecallantide (Kalbitor®), regardless of your age or weight. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Recommended Ecallantide Dosing Guidelines

The recommended dose for treating hereditary angioedema (HAE) attacks in people 12 years of age and older is three 10-mg (1 mL) injections under the skin (subcutaneously), for a total of 30 mg (3 mL) of ecallantide. Another dose (three injections) may be given if the HAE attack continues. This must be given within 24 hours of the first dose. 

General Information on Using Ecallantide

Some considerations to keep in mind during treatment with ecallantide include the following:
  • This medication is given as an injection just under the skin (as a subcutaneous injection).
  • Ecallantide injections are given by a healthcare provider. They may be given in a healthcare setting or in your home.
  • The injections are usually given in the fatty layer of the abdomen (the "stomach" area), thigh, or upper arm.
  • All three injections can be given in the same part of your body (abdomen, thigh, or upper arm), but the injection sites should be separated by at least two inches.
  • Injection sites should be away from the site of the HAE attack.
  • For this drug to work properly, it must be used as prescribed.
  • If you are unsure about anything related to your dosage of ecallantide, please talk with your healthcare provider, nurse, or pharmacist.

Ecallantide Drug Information

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