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What Should I Tell My Healthcare Provider Before Using It?

You should talk with your healthcare provider prior to taking dronedarone if you have:
  • Severe or prolonged diarrhea or vomiting
  • Low electrolytes (such as low potassium levels)
  • Long QT syndrome
  • Peripheral artery disease (PAD)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Heart failure
  • Sick sinus syndrome
  • A slow heart rate (bradycardia)
  • Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Dronedarone to learn more, including information on who should not take the drug.)

How Does Dronedarone Work?

It is not yet clear exactly how dronedarone works to treat arrhythmias. Most arrhythmia medications are classified using the Vaughn-Williams classification system, which divides arrhythmia medications into four classes depending on how they work. At this point, it seems that dronedarone has activity that belongs to all four of the classes.

Effects of Dronedarone

This medication has been thoroughly studied in various clinical trials. In general, these studies showed that dronedarone was more effective than a placebo (a "sugar pill" with no active ingredients) for preventing heart-related hospitalizations. Some studies also showed that dronedarone could delay the time until the first recurrence of atrial fibrillation or atrial flutter.
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Dronedarone Drug Information

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