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Drug Interactions With Doxylamine and Pyridoxine

More Detail on Drug Interactions With Doxylamine and Pyridoxine

The following sections explain in detail the potentially negative reactions that can occur when any of the drugs mentioned above are combined with doxylamine and pyridoxine.
 
Alcohol
Doxylamine and pyridoxine can cause drowsiness. Taking it with alcohol can add to this effect, which could increase your risk for falls or other accidents. It is recommended that women taking doxylamine and pyridoxine not drink alcohol. 
 
Anticholinergic Medications
Combining doxylamine and pyridoxine with anticholinergic medications could increase your risk for developing side effects (known as anticholinergic effects), such as:
 
  • Constipation
  • Dry mouth
  • Dry eyes
  • A fast heart rate
  • Urinary retention (difficulty passing urine).
 
Medications That Cause Drowsiness
Doxylamine and pyridoxine can cause drowsiness. Combining it with other medicines that cause drowsiness may increase this effect, which could increase your risk for falls or other accidents. People taking doxylamine and pyridoxine are recommended to not take other medicines that can cause drowsiness.
 
Monoamine Oxidase Inhibitors (MAOIs)
Taking doxylamine and pyridoxine with an MAOI may worsen and prolong certain side effects known as anticholinergic effects, such as:
 
  • Drowsiness
  • Dry mouth
  • Constipation
  • Dry eyes
  • Difficulty passing urine.
 
Doxylamine and pyridoxine should not be taken in combination with an MAOI.
 

Final Thoughts

It is possible that not all doxylamine and pyridoxine drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
 
Pregnancy and Pain

Doxylamine and Pyridoxine Drug Information

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