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Drug Interactions

There are a number of medications that may potentially interact with donepezil.
(Click Drug Interactions With Donepezil for more information.)

Alternatives to Donepezil

For most people, donepezil is quite effective in treating the symptoms of Alzheimer's disease. It is also generally well tolerated. Side effects can occur, however, and people may wish to consider a substitute for donepezil. These substitutes could include other acetylcholinesterase inhibitors or other medications used in the treatment of Alzheimer's.


People who take too much donepezil may experience the following symptoms:
  • Severe nausea and vomiting
  • Sweating
  • Salivation (increased watering of the mouth)
  • Slowed heart beat (bradycardia)
  • Low blood pressure (hypotension)
  • Troubled breathing
  • Respiratory depression or collapse
  • Convulsions (seizures).
If you happen to overdose on donepezil, seek medical attention immediately.
(Click Aricept Overdose for more information.)

Storage Methods for Donepezil

Donepezil should be stored at room temperature in a tightly closed container. It should be protected from light and moisture. Do not store in the bathroom, near the kitchen sink, or in other damp places.
Throw away any unused medication after the expiration date. Ask your healthcare provider or pharmacist how you should dispose of donepezil.
Keep donepezil and all medications out of the reach of children.
5 Tips to Reduce Your Risk of Alzheimer's

Donepezil HCl

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