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Drug Interactions With Dolasetron

Dolasetron Interactions Explained

Each of the medications listed above (except atenolol, cimetidine, and rifampin) increases the risk of a dangerous irregular heart rhythm (arrhythmia) called QT prolongation. Since dolasetron can also increase the risk for QT prolongation, it should generally not be combined with any of the medications listed above. There may be some instances when it may be appropriate to use dolasetron with these medications, especially if the heart is monitored closely. Since this list does not include all QT-prolonging medications, it is very important to tell your healthcare provider about every medication you are taking. Diuretics are not technically QT-prolonging medications, but some diuretics may cause low potassium or magnesium in your blood, which may put you at risk for arrhythmias.
Atenolol (Tenormin) and cimetidine (Tagamet) can increase the level of dolasetron in your blood, increasing your risk of dolasetron side effects. Rifampin (Rifadin) can decrease the level of dolasetron in your blood, making it less effective. Your healthcare provider may need to adjust your dolasetron dosage if you are taking one of these medications.

Final Thoughts on Dolasetron Drug Interactions

It is possible that not all dolasetron drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with dolasetron that may apply to you.
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