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Dolasetron Dosing

To help prevent nausea and vomiting that may occur with surgery, dolasetron may be given intravenously (by IV) about 15 minutes before the end of anesthesia. Dosing for children ages 2 to 16 is based on the child's weight. For the prevention of nausea and vomiting due to chemotherapy, the recommended dolasetron dosage is 100 mg taken within one hour before chemotherapy.

Dolasetron Dosage: An Introduction

The dose of dolasetron mesylate (Anzemet®) that your healthcare provider recommends will vary depending on a number of factors, including:
 
  • Your age and weight
  • Whether you are having surgery or chemotherapy
  • Other medications you may be taking
  • Other medical conditions you may have.
     
As is always the case, do not adjust your dolasetron dose unless your healthcare provider specifically instructs you to do so.
 

Dolasetron Dosing for Surgery

For preventing nausea and vomiting due to surgery, dolasetron is given by IV about 15 minutes before the end of anesthesia. If it isn't given during surgery, a dose can be given at any time after surgery if nausea or vomiting develop.
 
For adults, the recommended dolasetron dosage for this purpose is 12.5 mg given intravenously (by IV).
 
For children ages 2 to 16, the recommended dose is based on weight -- dolasetron 0.35 mg per kg of body weight (about 0.16 mg per pound).
 
Dolasetron tablets are not approved for this use. 
 

Dolasetron Dosing for Chemotherapy

For adults, the recommended dolasetron dose for the prevention of nausea and vomiting due to chemotherapy is 100 mg taken by mouth within one hour before chemotherapy. For children ages 2 to 16, the recommended dose is based on weight -- dolasetron 1.8 mg per kg of body weight (about 0.8 mg per pound) taken by mouth within one hour before chemotherapy.
 
The injectable form of dolasetron is not approved for this use. 
 
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Dolasetron Mesylate -- Drug Information

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