Precautions and Warnings With Dextromethorphan and Quinidine

You may not be able to safely take dextromethorphan and quinidine if you have certain medical conditions, such as high blood pressure, heart problems, or Alzheimer's disease. Other precautions and warnings with dextromethorphan and quinidine involve the danger of potentially serious drug interactions, the risk of developing heart rhythm problems, and the safety of using it when pregnant or breastfeeding.

Dextromethorphan and Quinidine Information

What Should I Tell My Healthcare Provider Before Taking Dextromethorphan and Quinidine?

You should talk with your healthcare provider prior to taking

dextromethorphan and quinidine (Nuedexta™) if you have:

Heart failure or coronary artery disease
A history of an abnormal electrocardiogram (ECG)
Heart rhythm problems, including QT prolongation or atrioventricular (AV) block
A family history of heart problems
High blood pressure, not controlled on medication
A history of a stroke
Myasthenia gravis, a condition that affects the muscles and nerves
Alzheimer's disease
Difficulty urinating (urinary retention)
Liver disease, such as hepatitis, cirrhosis, or liver failure
Any allergies, including to foods, dyes, or preservatives.

Also, let your healthcare provider know if you are:

Pregnant or thinking of becoming pregnant
Breastfeeding.

Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

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