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Drug Interactions With Dextromethorphan and Quinidine

Tamsulosin
Taking dextromethorphan and quinidine with tamsulosin can increase the level of tamsulosin in your blood, increasing your risk for serious side effects. In general, these medications should not be used together.
 
Theophylline
Dextromethorphan and quinidine may increase the level of theophylline in the blood, potentially increasing your risk for side effects. If you take these medications together, your healthcare provider may choose to monitor you more closely. You may need a lower theophylline dose.
 
Tolvaptan
Combining dextromethorphan and quinidine with tolvaptan can raise the level of tolvaptan in your blood, increasing your risk for serious side effects. In general, these medications should not be used together.
 
Topotecan
Taking dextromethorphan and quinidine with topotecan may raise the level of tolvaptan in your blood, increasing your risk for serious side effects. In general, these medications should not be used together.
 
Tramadol
Taking dextromethorphan and quinidine with tramadol can increase your risk for a serious reaction known as serotonin syndrome (see Precautions and Warnings With Dextromethorphan and Quinidine for more information, including symptoms of serotonin syndrome). Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome.
 
Triptans
Taking dextromethorphan and quinidine with triptans can increase your risk for a serious reaction known as serotonin syndrome (see Precautions and Warnings With Dextromethorphan and Quinidine for more information, including symptoms of serotonin syndrome). Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome.
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Dextromethorphan and Quinidine Information

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